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4-Amino-2-methoxy-5-pyrimidinemethanol; 4-Amino-5-hydroxymethyl-2-methoxypyrimidine
Chemical
C6H9N3O2
155.2
12: 00964
3690-12-8
Isolated from Streptomyces albus.
≥98% (HPLC)
Off-white powder.
Soluble in DMSO or methanol.
Determined by 1H-NMR.
Manufactured by BioViotica.
ZPNHGSNYBLXGOL-UHFFFAOYSA-N
AMBIENT
+4°C
-20°C
Stable for at least 1 year after receipt when stored at -20°C.After reconstitution protect from light at -20°C.
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  • Derivative of 5-Hydoxymethylcytosine (Prod. No. BVT-0229).
  • Antibiotic.
  • Antibacterial.
  • Thiamine antagonist.
  • Phosphatase kinase inhibitor
Product References
  • Biological studies on bacimethrin, a pyrimidine antibiotic, and monazomycin: T. Nishimura & N. Tanaka; J. Antibiot. 16, 179 (1963)
  • Bacimethrin isolated from Streptomyces albus identification, derivatives, synthesis and biological properties: H. Drautz, et al.; J. Antibiot. 40, 1431 (1987)
  • Nucleoside antibiotics: Structure, biological activity, and biosynthesis: K. Isono; J. Antibiot. 41, 1711 (1988) (Review)
  • The mechanism of action of bacimethrin, a naturally occurring thiamin antimetabolite: J.J. Reddick, et al.; Bioorg. Med. Chem. Lett. 11, 2245 (2001)
  • Hydrophilic modifications in peptide nucleic acid - Synthesis and properties of PNA possessing 5-hydroxymethyluracil and 5-hydroxymethylcytosine: R.H.E. Hudson, et al.; Can. J. Chem. 85, 302 (2007)